Research projects

Research projects

In order to provide our Patients with effective and safe treatments, we not only closely follow all the new trends in medicine, but also conduct, in cooperation with the most renowned academic centres, our own research. Our projects are regularly approved and co-financed by government institutions. Below you will find information concerning our current research projects.

Projekty naukowe Timeless Chirurgia Plastyczna

The aim of the project is to develop the use of adipose-derived stem cells (ADSC) in regenerative medicine. The project will include two types of research activity. Within “from laboratory to clinic” path we will use our knowledge and skills to prepare ADSC to clinical trials planned within the framework of the project: in the treatment of diabetic foot as well as aesthetic medicine (patients with scars and aging of the skin.) In “from laboratory to stem cell banking and innovative preparation of stem cells application” path we are planning to implement ADSC banking service involving individual characteristics of differentation potential of each deposited cell population. 

We will search for the correlation between ADSC differentiation in stem cell culture and the results of transcriptomic and epigenomic analysis of cells as a quick method of evaluating the differentiation potential of the deposited cells. We will test new methods of preparing ADSC to application through the following techniques: mixed stem cells with different phenotypes derived from one population culture, connecting with biomaterials as cell carriers and “macromolecular crowding”. We will also test immunogenic character of human ADSC for the future use in GvHD (graft-versus-host disease) and in allogenic applications. The know-how generated by two academic centres will be validated and prepared to being implemented by four commercial partners.

The aim of the project is to set up an innovative method of regeneration of large bone tissue loss in oncological patients, based on the use of scaffold for tissue engineering and in vivo tissue engineering (iTE.) In this method, after the first stage of removing the bone tumour, an advanced refillment element (spacer) releasing antibacterial medicines and supporting radio and/or chemotherapy will be implemented in the area of the bone loss.

Simultaneously, advanced bioactive and biodegradable scaffold will be ectopically injected into the patient’s body, in the area supporting the formation of new tissue. After the in vivo creation of new bone tissue, the spacer will be removed and a prefabricated tissue flap (a product of tissue engineering) will be grafted and implemented in the area of mandible loss, ensuring its physiological and aesthetic functionality. To achieve this aim, an advanced spacer, a bioactive scaffold and a method of supplying them with bioactive agents will be worked out.

The results of the project will be tested in vitro and in vivo on small and big animal models.